Effect of age on plasma 1,25-(OH)2 vitamin D in the rat

Richard W. Gray, Steven R. Gambert

Research output: Contribution to journalArticle

Abstract

Levels of plasma calcium, phosphorus, creatinine and 1,25-(OH)2-D were measured in healthy male Sprague-Dawley rats aged 6 months (mature) and 20-24 months (senescent). Plasma 1,25-(OH)2-D levels fell from 95 ± 50 pmol/l in the mature rats to 41 ± 10 pmol/l in the senescent rats (p <0.01). Despite a significant fall in plasma phosphate from 3.06 ± 0.37 mmol/l to 2.54 mmol/l (p <0.005) in the two groups, respectively, plasma calcium remained constant at about 2.4 mmol/l in both groups.

Original languageEnglish (US)
Pages (from-to)54-56
Number of pages3
JournalAge
Volume5
Issue number2
DOIs
Publication statusPublished - Apr 1982
Externally publishedYes

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ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology
  • Medicine(all)

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