Effect of age and alcohol consumption on plasma lipids in the rat

Steven R. Gambert, Joseph J. Barboriak

Research output: Contribution to journalArticlepeer-review

Abstract

Rats aged 6 weeks (young), 6 months (mature), and 20 months (senescent) were offered alcohol ad libitum for 3 weeks to study the interrelationship between alcohol, age, and serum lipids. Although the total quantity of alcohol consumption increased with age, senescent rats actually consumed less alcohol per gram body weight per day as compared to either mature or young rats. Increasing age alone was associated with higher levels of total serum cholesterol and high-density lipoprotein cholesterol. Triglyceride levels were not affected by age. Alcohol consumption elevated high density lipoprotein cholesterol in young rats, however, did not alter this lipid fraction in either mature or senescent rats. Triglyceride levels were elevated by alcohol only in senescent rats.

Original languageEnglish (US)
Pages (from-to)85-87
Number of pages3
JournalAGE
Volume4
Issue number3
DOIs
StatePublished - Jul 1 1981

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

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