Effect of 0.5% apraclonidine on ptosis in Horner syndrome

Daniel C. Garibaldi, Holly B. Hindman, Michael P. Grant, Nicholas T. Iliff, Shannath L. Merbs

Research output: Contribution to journalArticlepeer-review


To demonstrate the effect of apraclonidine on anisocoria and ptosis in Horner syndrome, one drop of 0.5% apraclonidine was instilled in both eyes of 3 patients who presented with acute Horner syndrome, and the effect on ptosis and anisocoria was documented. As reported in the literature, one drop of 0.5% apraclonidine reverses the anisocoria of Horner syndrome. In addition, 0.5% apraclonidine leads to a complete resolution of the ptosis associated with Horner syndrome, a finding reported once in the literature. Apraclonidine is a safe and readily available alternative to cocaine for the diagnosis of Horner syndrome.

Original languageEnglish (US)
Pages (from-to)53-55
Number of pages3
JournalOphthalmic plastic and reconstructive surgery
Issue number1
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


Dive into the research topics of 'Effect of 0.5% apraclonidine on ptosis in Horner syndrome'. Together they form a unique fingerprint.

Cite this