Effect of β-funaltrexamine on retention of passive-avoidance conditioning

Research output: Contribution to journalArticlepeer-review

Abstract

Rats received administration of an opiate antagonist immediately following single-trial passive-avoidance training. Retention of passive-avoidance conditioning was assessed 1 week after training. Compared to noninjected and vehicle-injected control groups, post-training naloxone (2.0 mg/kg) administration significantly increased retention. A comparable facilitation of retention was also observed when animals received post-training administration of β-funaltrexamine (40 mg/kg). These data provide additional support for mu opiate receptor activity in the regulation of memory processes.

Original languageEnglish (US)
Pages (from-to)499-502
Number of pages4
JournalBehavioral and Neural Biology
Volume44
Issue number3
DOIs
StatePublished - Nov 1985
Externally publishedYes

ASJC Scopus subject areas

  • Physiology

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