EEG power spectra in huntington's disease: Clinical and neuropsychological correlates

F. W. Bylsma, C. E. Peyser, S. E. Folstein, C. Ross, J. Brandt

Research output: Contribution to journalArticle

Abstract

Quantitative power spectral analysis (PSA) was applied to frontal (F3, F4, F7, F8), temporal (T5, T6), and occipital (O1, O2) EEGs of 16 Huntington's disease (HD) patients and eight healthy control subjects. PSA revealed HD patients' EEGs to be abnormal: (i) raw and percent Alpha power were reduced; (ii) raw and percent Theta power were reduced at F3 and F4; (iii) percent Delta and percent Beta power were increased; (iii) Theta frequency was reduced by ~1.0 Hz. Frontal and temporal EEG power measures and decreased EEG amplitude correlated with severity of neurological and cognitive impairment.

Original languageEnglish (US)
Pages (from-to)137-150
Number of pages14
JournalNeuropsychologia
Volume32
Issue number2
DOIs
StatePublished - Feb 1994

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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