Editorial: Bugs and drugs: Insights into the pathogenesis of inflammatory bowel disease

Geoffrey C. Nguyen

Research output: Contribution to journalReview articlepeer-review

Abstract

The dysbiosis hypothesis posits that perturbations in the gut microbiome may contribute to the development of inflammatory bowel disease (IBD). A recent Canadian population-based study has shown an association between new-onset IBD and antibiotic use in the 2-5 years preceding diagnosis. Though these findings do not establish a causal relationship, it supports the role of dysbiosis in the pathogenesis of IBD. Furthermore, the study reinforces the importance of the judicious use of antibiotics.

Original languageEnglish (US)
Pages (from-to)2143-2145
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume106
Issue number12
DOIs
StatePublished - Dec 1 2011

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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