Histologic study of the hypophyseal component of a benign cystic ovarian teratoma disclosed elements that resembled sellar adenohypophysis, pars intermedia, and neurohypophysis. Histochemical dye methods revealed secretory cells with cytologic and granule-staining characteristics of somatotrophs, mammotrophs, melanocorticotrophs, and thyrotrophs. Nongranulated follicular cells and salivary gland rest cells also were present. Indirect immunoperoxidase staining with monospecific antisera to anterior pituitary hormones revealed abundant prolactin-containing cells, which comprised more than 50% of all chromophilic cells, as well as numerous cells that contained growth hormone and thyroid stimulating hormone. Gonadotrophic cells could not be demonstrated by either tinctorial stains or immunostaining.
|Original language||English (US)|
|Number of pages||7|
|Journal||Archives of Pathology and Laboratory Medicine|
|State||Published - Jan 1 1978|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology