Ecological and evolutionary forces shaping microbial diversity in the human intestine

Ruth E. Ley, Daniel A. Peterson, Jeffrey I. Gordon

Research output: Contribution to journalArticle

Abstract

The human gut is populated with as many as 100 trillion cells, whose collective genome, the microbiome, is a reflection of evolutionary selection pressures acting at the level of the host and at the level of the microbial cell. The ecological rules that govern the shape of microbial diversity in the gut apply to mutualists and pathogens alike.

Original languageEnglish (US)
Pages (from-to)837-848
Number of pages12
JournalCell
Volume124
Issue number4
DOIs
StatePublished - Feb 24 2006
Externally publishedYes

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Pathogens
Intestines
Genes
Microbiota
Genome
Pressure

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Ecological and evolutionary forces shaping microbial diversity in the human intestine. / Ley, Ruth E.; Peterson, Daniel A.; Gordon, Jeffrey I.

In: Cell, Vol. 124, No. 4, 24.02.2006, p. 837-848.

Research output: Contribution to journalArticle

Ley, Ruth E. ; Peterson, Daniel A. ; Gordon, Jeffrey I. / Ecological and evolutionary forces shaping microbial diversity in the human intestine. In: Cell. 2006 ; Vol. 124, No. 4. pp. 837-848.
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