TY - JOUR
T1 - Echocardiographic nomograms for upper abdominal aorta Doppler systolic wave values and systo-diastolic diameters variations in children
AU - Cantinotti, Massimiliano
AU - Giordano, Raffaele
AU - Corsini, Iuri
AU - Dani, Carlo
AU - Scalese, Marco
AU - Murzi, Bruno
AU - Assanta, Nadia
AU - Spadoni, Isabella
AU - Molinaro, Sabrina
AU - Kutty, Shelby
AU - Iervasi, Giorgio
AU - Franchi, Eliana
N1 - Funding Information:
The work has been supported by Italian Health Ministry Finalized Research Young Research Award 2011 Project No. GR-211-02350662.
Publisher Copyright:
© 2017 Japanese College of Cardiology
PY - 2018/4
Y1 - 2018/4
N2 - Background: Abdominal aorta pulsatility and blood flow patterns are important diagnostic indicators in congenital heart disease. Reference values for these indexes are lacking. Methods: We prospectively studied abdominal aorta pulsed-wave Doppler systolic peak velocity, deceleration time, and wave duration, and two-dimensional vessel diameters in systole and diastole in healthy Caucasian children. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate (HR), and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. Results: In all, 853 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12 m 2 ) were studied. The predicted values and Z-score boundaries are presented. Data are also presented as mean ± 2 SDs for a given BSA. Conclusions: We report paediatric echocardiographic nomograms for multiple proximal abdominal aorta parameters including pulsed-wave Doppler systolic velocities, deceleration time, wave duration, and two-dimensional vessel diameter variations. Significant variations in these functional indexes with age were found that should be taken into account in clinical practice. At lower ages, steeper and shorter pulsed-wave Doppler peak velocity and limited pulsatility should be expected as physiologic findings.
AB - Background: Abdominal aorta pulsatility and blood flow patterns are important diagnostic indicators in congenital heart disease. Reference values for these indexes are lacking. Methods: We prospectively studied abdominal aorta pulsed-wave Doppler systolic peak velocity, deceleration time, and wave duration, and two-dimensional vessel diameters in systole and diastole in healthy Caucasian children. Heteroscedasticity was accounted for by White or Breusch–Pagan test. Age, weight, height, heart rate (HR), and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. Structured Z-scores were then computed. Results: In all, 853 subjects (age 0 days to 17 years; 45% females; BSA 0.12–2.12 m 2 ) were studied. The predicted values and Z-score boundaries are presented. Data are also presented as mean ± 2 SDs for a given BSA. Conclusions: We report paediatric echocardiographic nomograms for multiple proximal abdominal aorta parameters including pulsed-wave Doppler systolic velocities, deceleration time, wave duration, and two-dimensional vessel diameter variations. Significant variations in these functional indexes with age were found that should be taken into account in clinical practice. At lower ages, steeper and shorter pulsed-wave Doppler peak velocity and limited pulsatility should be expected as physiologic findings.
KW - Children
KW - Echocardiography
KW - Nomograms
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U2 - 10.1016/j.jjcc.2017.09.016
DO - 10.1016/j.jjcc.2017.09.016
M3 - Article
C2 - 29129395
AN - SCOPUS:85033598782
SN - 0914-5087
VL - 71
SP - 394
EP - 400
JO - Journal of Cardiology
JF - Journal of Cardiology
IS - 4
ER -