Abstract
The effect of host immune status on SARS-CoV-2 infection remains unknown. Here, we report the first case of COVID-19 with HIV-1 and HCV co-infection, who showed a persistently negative SARS-CoV-2 RNA test, but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on the early SARS-CoV-2 clearance.
| Original language | English (US) |
|---|---|
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| DOIs | |
| State | Accepted/In press - Apr 9 2020 |
Keywords
- Antibody
- COVID-19
- HCV
- HIV-1
- SARS-CoV-2
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases
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Zhao, J., Liao, X., Wang, H., Wei, L., Xing, M., Liu, L., & Zhang, Z. (Accepted/In press). Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. https://doi.org/10.1093/cid/ciaa408