Tendências iniciais e preditores de função renal após crioablação percutânea guiada por tomografia computadorizada de massa renal em pacientes com e sem comprometimento renal prévio

Translated title of the contribution: Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment

Pedro V. Staziaki, Harshna V. Vadvala, Vanessa Fiorini Furtado, Dania Daye, Ronald S. Arellano, Raul N. Uppot

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To assess trends and predictors of the glomerular filtration rate (GFR) after renal mass cryoablation in patients with and without history of renal impairment. Materials and Methods: This was a retrospective study of 39 patients who underwent computed tomography-guided percutaneous cryoablation of a renal mass, divided into two groups: those with prior renal impairment (PRI+); and those without prior renal impairment (PRI−). The GFR trend and the chronic kidney disease stage were evaluated at baseline, as well as at 1, 6, and 12 months after cryoablation. Predictors of GFR at 1 and 6 months were modeled with linear regression. Results: In both groups, the mean GFR at 1 month and 6 months was significantly lower than at baseline (p < 0.001 and p = 0.01, respectively). Although the GFR was lower across all time points in the PRI+ group (−26.1; p < 0.001), the overall trend was not statistically different from that observed in the PRI− group (p = 0.89). Univariate analysis showed that the decline in GFR at 1 and 6 months correlated with the baseline GFR (0.77 and 0.63; p < 0.001 and p = 0.03, respectively) and with the size of the ablation zone (−7.6 and −12.84, respectively; p = 0.03 for both). However, in the multivariate model, baseline GFR was predictive only of GFR at 1 month (p < 0.001). Conclusion: The trend in GFR decline after cryoablation is similar for patients with and without a history of renal impairment. Baseline GFR predicts the mean GFR in the early post-cryoablation period.

Translated title of the contributionEarly trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment
Original languagePortuguese
Pages (from-to)141-147
Number of pages7
JournalRadiologia Brasileira
Volume53
Issue number3
DOIs
StatePublished - May 1 2020

Keywords

  • Glomerular filtration rate
  • Interventional
  • Kidney/physiopathology
  • Radiology
  • Renal insufficiency
  • Tomography
  • X-ray com-puted/methods

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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