Early-onset scleral necrosis after iodine I 125 plaque radiotherapy for ciliochoroidal melanoma

Zélia M. Corrêa, James J. Augsburger, Jorge Freire, Ralph C. Eagle

Research output: Contribution to journalArticlepeer-review

Abstract

A 62-year-old man with a large ciliochoroidal melanoma developed early- onset scleral necrosis with tumor extrusion within 1 month of epibulbar iodine I 125 plaque radiotherapy. The eye was enucleated. Pathologic study revealed nonmicrobial scleral necrosis with extrusion of histologically intact and necrotic uveal melanoma cells. The patient has been followed up for 15 months without clinical recurrence. We discuss possible mechanisms to explain the early development of scleral necrosis after plaque therapy in this patient.

Original languageEnglish (US)
Pages (from-to)259-261
Number of pages3
JournalArchives of ophthalmology
Volume117
Issue number2
DOIs
StatePublished - Feb 1999

ASJC Scopus subject areas

  • Ophthalmology

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