Early Management of Acute Spinal Cord Injury-Part I: Initial Injury to Surgery

Amanda Sacino, Kathryn Rosenblatt

Research output: Contribution to journalReview articlepeer-review


Acute spinal cord injury is a devastating event associated with substantial morbidity worldwide. The pathophysiology of spinal cord injury involves the initial mechanical trauma and the subsequent inflammatory response, which may worsen the severity of neurologic dysfunction. Interventions have been studied to reduce the extent of primary injury to the spinal cord through preventive measures and to mitigate secondary insult through early specialized care. Management, therefore, is multifold, interdisciplinary, and begins immediately at the time of injury. It includes the trauma triage, acute management of the circulatory and respiratory systems, and definitive treatment, mainly with surgical decompression and stabilization.

Original languageEnglish (US)
Article numberJNACC1900123
Pages (from-to)213-221
Number of pages9
JournalJournal of Neuroanaesthesiology and Critical Care
Issue number3
StatePublished - Sep 1 2019


  • airway management
  • blood pressure targets
  • bradycardia
  • intraoperative neuromonitoring
  • neurogenic shock
  • respiratory arrest
  • resuscitation
  • spinal cord injury
  • spinal shock
  • surgical decompression

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Critical Care and Intensive Care Medicine
  • Clinical Neurology


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