Early imaging of experimental intestinal infarction with 99mTc-pyrophosphate

K. H. Barth, P. O. Alderson, J. D. Strandberg, J. W. Fara

Research output: Contribution to journalArticlepeer-review

Abstract

Extensive mucosal small-bowel infarction was produced in 8 dogs by occluding the cranial mesenteric artery. After one hour of reperfusion, 15 mCi (555 MBq) of 99mTc-pyrophosphate was intra-arterially injected into 4 dogs and venously into the other 4. Positive images were obtained in all dogs except 1 which had received an intravenous injection. Diagnostic images were obtained consistently as early as 15 minutes after injection, and the infarcted bowel could still be visualized two hours later. The average tracer content in infarcted small bowel was 0.015% I.D./g. This was about eight times the uptake found in normal dogs. The results show that experimental small-bowel infarction can be detected as early as five hours after the onset of ischemia.

Original languageEnglish (US)
Pages (from-to)459-462
Number of pages4
JournalRADIOLOGY
Volume133
Issue number2
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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