Early detection of retinal involvement in diabetes by vitreous fluorophotometry

J. G. Cunha-Vaz, Morton F Goldberg, C. Vygantas, J. Noth

Research output: Contribution to journalArticle

Abstract

Vitreous fluorophotometry is a new quantitative method for evaluation of the blood-retinal barrier (BRB). The application of this method to a series of diabetic patients with apparently normal fundi revealed the presence of a significant breakdown of the BRB in the early stages of retinal involvement in diabetes. This alteration of the BRB appears to be the earliest clinically detectable change to occur in the retina in diabetes. Higher vitreous fluorophotometry values, indicating a more marked breakdown of the BRB, occurred in patients who were under worse metabolic control. Higher vitreous fluorophotometry values were also associated with the development of visible retinal lesions.

Original languageEnglish (US)
Pages (from-to)264-275
Number of pages12
JournalOphthalmology
Volume86
Issue number2
StatePublished - 1979
Externally publishedYes

Fingerprint

Fluorophotometry
Blood-Retinal Barrier
Retina

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Early detection of retinal involvement in diabetes by vitreous fluorophotometry. / Cunha-Vaz, J. G.; Goldberg, Morton F; Vygantas, C.; Noth, J.

In: Ophthalmology, Vol. 86, No. 2, 1979, p. 264-275.

Research output: Contribution to journalArticle

Cunha-Vaz, JG, Goldberg, MF, Vygantas, C & Noth, J 1979, 'Early detection of retinal involvement in diabetes by vitreous fluorophotometry', Ophthalmology, vol. 86, no. 2, pp. 264-275.
Cunha-Vaz, J. G. ; Goldberg, Morton F ; Vygantas, C. ; Noth, J. / Early detection of retinal involvement in diabetes by vitreous fluorophotometry. In: Ophthalmology. 1979 ; Vol. 86, No. 2. pp. 264-275.
@article{b40d6417f53346c79731da4fba9a2bbe,
title = "Early detection of retinal involvement in diabetes by vitreous fluorophotometry",
abstract = "Vitreous fluorophotometry is a new quantitative method for evaluation of the blood-retinal barrier (BRB). The application of this method to a series of diabetic patients with apparently normal fundi revealed the presence of a significant breakdown of the BRB in the early stages of retinal involvement in diabetes. This alteration of the BRB appears to be the earliest clinically detectable change to occur in the retina in diabetes. Higher vitreous fluorophotometry values, indicating a more marked breakdown of the BRB, occurred in patients who were under worse metabolic control. Higher vitreous fluorophotometry values were also associated with the development of visible retinal lesions.",
author = "Cunha-Vaz, {J. G.} and Goldberg, {Morton F} and C. Vygantas and J. Noth",
year = "1979",
language = "English (US)",
volume = "86",
pages = "264--275",
journal = "Ophthalmology",
issn = "0161-6420",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Early detection of retinal involvement in diabetes by vitreous fluorophotometry

AU - Cunha-Vaz, J. G.

AU - Goldberg, Morton F

AU - Vygantas, C.

AU - Noth, J.

PY - 1979

Y1 - 1979

N2 - Vitreous fluorophotometry is a new quantitative method for evaluation of the blood-retinal barrier (BRB). The application of this method to a series of diabetic patients with apparently normal fundi revealed the presence of a significant breakdown of the BRB in the early stages of retinal involvement in diabetes. This alteration of the BRB appears to be the earliest clinically detectable change to occur in the retina in diabetes. Higher vitreous fluorophotometry values, indicating a more marked breakdown of the BRB, occurred in patients who were under worse metabolic control. Higher vitreous fluorophotometry values were also associated with the development of visible retinal lesions.

AB - Vitreous fluorophotometry is a new quantitative method for evaluation of the blood-retinal barrier (BRB). The application of this method to a series of diabetic patients with apparently normal fundi revealed the presence of a significant breakdown of the BRB in the early stages of retinal involvement in diabetes. This alteration of the BRB appears to be the earliest clinically detectable change to occur in the retina in diabetes. Higher vitreous fluorophotometry values, indicating a more marked breakdown of the BRB, occurred in patients who were under worse metabolic control. Higher vitreous fluorophotometry values were also associated with the development of visible retinal lesions.

UR - http://www.scopus.com/inward/record.url?scp=0018764456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018764456&partnerID=8YFLogxK

M3 - Article

VL - 86

SP - 264

EP - 275

JO - Ophthalmology

JF - Ophthalmology

SN - 0161-6420

IS - 2

ER -