Early antigen titers in pediatric patients with acute cervical lymphadenitis

E. L. Boyd, J. E. McClung, R. W. Veltri, P. M. Sprinkle

Research output: Contribution to journalArticlepeer-review

Abstract

Eight pediatric patients with acute cervical lymphadenitis or neck mass, alone or in association with nonspecific upper respiratory complaints, were screened for the presence of a primary or reactivation Epstein-Barr virus infection. All were found to have elevated antibodies to the early antigen (EA) and 75% (6) of these were found to be reactivations. Only one had a positive heterophile. Half of the patients had elevation of the EA-specific IgA, and 75% (6) had elevation of viral capsid antigen-specific IgA. All had elevated levels of soluble immune complexes. There was not a direct relationship between the EA titer or soluble immune complex level and severity of disease.

Original languageEnglish (US)
Pages (from-to)6-10
Number of pages5
JournalOtolaryngology - Head and Neck Surgery
Volume90
Issue number1
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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