Early antigen titers in pediatric patients with acute cervical lymphadenitis

E. L. Boyd; J. E. McClung; R. W. Veltri; P. M. Sprinkle

doi:10.1177/019459988209000102

Early antigen titers in pediatric patients with acute cervical lymphadenitis

E. L. Boyd, J. E. McClung, R. W. Veltri, P. M. Sprinkle

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Eight pediatric patients with acute cervical lymphadenitis or neck mass, alone or in association with nonspecific upper respiratory complaints, were screened for the presence of a primary or reactivation Epstein-Barr virus infection. All were found to have elevated antibodies to the early antigen (EA) and 75% (6) of these were found to be reactivations. Only one had a positive heterophile. Half of the patients had elevation of the EA-specific IgA, and 75% (6) had elevation of viral capsid antigen-specific IgA. All had elevated levels of soluble immune complexes. There was not a direct relationship between the EA titer or soluble immune complex level and severity of disease.

Original language	English (US)
Pages (from-to)	6-10
Number of pages	5
Journal	Otolaryngology - Head and Neck Surgery
Volume	90
Issue number	1
DOIs	https://doi.org/10.1177/019459988209000102
State	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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abstract = "Eight pediatric patients with acute cervical lymphadenitis or neck mass, alone or in association with nonspecific upper respiratory complaints, were screened for the presence of a primary or reactivation Epstein-Barr virus infection. All were found to have elevated antibodies to the early antigen (EA) and 75% (6) of these were found to be reactivations. Only one had a positive heterophile. Half of the patients had elevation of the EA-specific IgA, and 75% (6) had elevation of viral capsid antigen-specific IgA. All had elevated levels of soluble immune complexes. There was not a direct relationship between the EA titer or soluble immune complex level and severity of disease.",

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AB - Eight pediatric patients with acute cervical lymphadenitis or neck mass, alone or in association with nonspecific upper respiratory complaints, were screened for the presence of a primary or reactivation Epstein-Barr virus infection. All were found to have elevated antibodies to the early antigen (EA) and 75% (6) of these were found to be reactivations. Only one had a positive heterophile. Half of the patients had elevation of the EA-specific IgA, and 75% (6) had elevation of viral capsid antigen-specific IgA. All had elevated levels of soluble immune complexes. There was not a direct relationship between the EA titer or soluble immune complex level and severity of disease.

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Early antigen titers in pediatric patients with acute cervical lymphadenitis

Abstract

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