Dynamics of mRNA entry into stress granules

Research output: Contribution to journalArticle

Abstract

Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

Original languageEnglish (US)
Pages (from-to)116-117
Number of pages2
JournalNature Cell Biology
Volume21
Issue number2
DOIs
StatePublished - Feb 1 2019

Fingerprint

Messenger RNA
Eukaryotic Cells
Proteins

ASJC Scopus subject areas

  • Cell Biology

Cite this

Dynamics of mRNA entry into stress granules. / Lee, Chih-Yung; Seydoux, Geraldine.

In: Nature Cell Biology, Vol. 21, No. 2, 01.02.2019, p. 116-117.

Research output: Contribution to journalArticle

@article{e9c2a36a3d4d44659597a5b6bb2ca178,
title = "Dynamics of mRNA entry into stress granules",
abstract = "Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.",
author = "Chih-Yung Lee and Geraldine Seydoux",
year = "2019",
month = "2",
day = "1",
doi = "10.1038/s41556-019-0278-5",
language = "English (US)",
volume = "21",
pages = "116--117",
journal = "Nature Cell Biology",
issn = "1465-7392",
publisher = "Nature Publishing Group",
number = "2",

}

TY - JOUR

T1 - Dynamics of mRNA entry into stress granules

AU - Lee, Chih-Yung

AU - Seydoux, Geraldine

PY - 2019/2/1

Y1 - 2019/2/1

N2 - Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

AB - Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

UR - http://www.scopus.com/inward/record.url?scp=85060437118&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85060437118&partnerID=8YFLogxK

U2 - 10.1038/s41556-019-0278-5

DO - 10.1038/s41556-019-0278-5

M3 - Article

C2 - 30664788

AN - SCOPUS:85060437118

VL - 21

SP - 116

EP - 117

JO - Nature Cell Biology

JF - Nature Cell Biology

SN - 1465-7392

IS - 2

ER -