Dynamics of mRNA entry into stress granules

Chih Yung Lee, Geraldine Seydoux

Research output: Contribution to journalArticlepeer-review

Abstract

Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

Original languageEnglish (US)
Pages (from-to)116-117
Number of pages2
JournalNature cell biology
Volume21
Issue number2
DOIs
StatePublished - Feb 1 2019

ASJC Scopus subject areas

  • Cell Biology

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