Dynamics of Ly49 expressing cytotoxic lymphocyte subsets in response to virus infection

Craig D. Peacock, Weixin Xu, Susan E. Stepp, Raymond M. Welsh

Research output: Contribution to journalReview articlepeer-review

Abstract

Viral infections induce first a loss and then an increase in natural killer (NK) and CD8+ T cells. NK cells expressing Ly49G2 were selectively expanded by several viruses and poly I:C. CD8+ T cells expressing Ly49G2 were selectively expanded by poly I:C and participated in the antigen-specific response to lymphocytic choriomeningitis virus.

Original languageEnglish (US)
Pages (from-to)1481-1490
Number of pages10
JournalMicrobes and Infection
Volume4
Issue number15
DOIs
StatePublished - Dec 2002

Keywords

  • CD8-Positive T lymphocytes
  • Killer cells
  • Ly-49 antigen
  • Natural

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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