Abstract
PDZ domains are common building blocks of scaffold proteins that enhance specificity and speed in signal transduction cascades. Although PDZ modules are often viewed as passive participants, Mishra et al. (2007) now show that a PDZ domain in INAD, a scaffold protein in photoreceptor cells of the fruit fly, undergoes a light-dependent conformational change, which has important consequences for signaling and animal behavior.
Original language | English (US) |
---|---|
Pages (from-to) | 19-21 |
Number of pages | 3 |
Journal | Cell |
Volume | 131 |
Issue number | 1 |
DOIs | |
State | Published - Oct 5 2007 |
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology