Dynamic MR-based respiratory motion compensation for hybrid PET/MR system

Shun Miao, Rui Liao, Gerald Moran, John Butler, Li Pan, Z. Jane Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes a novel respiratory motion compensation (MC) technique for hybrid PET/MR system. Existing PET/MR respiratory MC techniques mainly rely on respiratory gating to reconstruct 3D MR images for different respiratory phases, and use image registration techniques to estimate the deformation between different respiratory phases. A well known limitation of respiratory gating is its assumption that breathing motion is perfectly periodic, therefore MC techniques based on gated MR are sensitive to irregular breathing patterns. To address this limitation, the proposed technique uses dynamic 2D MRIs for PET/MR respiratory motion estimation. A static 3D MRI and a series of dynamic 2D MRIs are acquired before and during the PET data acquisition, respectively. The dynamic 2D MRIs are registered against the static 3D MRI using a novel deformable 2D+t to 3D image registration method to derive a 3D+t deformation field, which is then used for motion corrected PET reconstruction. The proposed method is validated on synthetic PET/MR data and real MR data, demonstrating its efficacy to compensate for irregular respiratory motion and to deblur the PET image.

Original languageEnglish (US)
Title of host publicationProceedings of the 2014 9th IEEE Conference on Industrial Electronics and Applications, ICIEA 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1915-1920
Number of pages6
ISBN (Electronic)9781479943166
DOIs
StatePublished - Oct 20 2014
Externally publishedYes
Event9th IEEE Conference on Industrial Electronics and Applications, ICIEA 2014 - Hangzhou, China
Duration: Jun 9 2014Jun 11 2014

Other

Other9th IEEE Conference on Industrial Electronics and Applications, ICIEA 2014
CountryChina
CityHangzhou
Period6/9/146/11/14

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Dynamic MR-based respiratory motion compensation for hybrid PET/MR system'. Together they form a unique fingerprint.

Cite this