Dynamic changes of cerebrospinal fluid in upright and recumbent shunted experimental animals

Shokei Yamada, Thomas B. Ducker, Phanor L. Perot

Research output: Contribution to journalArticle

Abstract

The effect of positional change on intracranial CSF pressure, valve flow rates and atrial pressures were studied in 40 experimental dogs. The flow rate with a 30 to 60 mm H2O Holter valve changed from the recumbent to the head-up position: during the first minute it increased 21/2 times and then progressively decreased to become stabilized 20-30 min later at a value slightly lower than the head-up value. At the same time pressure dropped rapidly to-23 mm H2O and then slowly, during 30 min to-120 mm H2O. In dogs without a shunt the pressure drop was initially similar to that of shunted dogs but recovered to almost the initial positive pressure in 30 min. The flow rate from a reservoir to the atrium through a shunt system when changing to the head-up position showed a siphon effect. Atrial pressure does not change with positioning. The findings were similar with cisternal-peritoneal shunts. Flow rate, therefore, increase in the head-up position. Negative intracranial CSF pressure was due to a siphon effect through the shunt system.

Original languageEnglish (US)
Pages (from-to)187-192
Number of pages6
JournalPediatric Neurosurgery
Volume1
Issue number2 3
DOIs
StatePublished - Jan 1 1975

Keywords

  • Holter valve
  • Position and flow through valve
  • Position and intracranial pressure with shunt
  • Position and intracranial pressure without shunt
  • Siphon effect

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Clinical Neurology

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