Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules

T. Ha; Th Enderle; D. S. Chemla; S. Weiss

doi:10.1109/2944.577342

Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules

T. Ha, Th Enderle, D. S. Chemla, S. Weiss

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.

Original language	English (US)
Pages (from-to)	1115-1128
Number of pages	14
Journal	IEEE Journal on Selected Topics in Quantum Electronics
Volume	2
Issue number	4
DOIs	https://doi.org/10.1109/2944.577342
State	Published - Dec 1996
Externally published	Yes

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering

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10.1109/2944.577342

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title = "Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules",

abstract = "Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.",

author = "T. Ha and Th Enderle and Chemla, {D. S.} and S. Weiss",

note = "Funding Information: Manuscript received October 3, 1996; revised December 19, 1996. This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under U.S. Department of Energy Contract DE-AC03-76SF00098 and by the Office of Naval Research under Contract N00014-95-F-0099.",

year = "1996",

month = dec,

doi = "10.1109/2944.577342",

language = "English (US)",

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T1 - Dual-molecule spectroscopy

T2 - Molecular rulers for the study of biological macromolecules

AU - Ha, T.

AU - Enderle, Th

AU - Chemla, D. S.

AU - Weiss, S.

N1 - Funding Information: Manuscript received October 3, 1996; revised December 19, 1996. This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under U.S. Department of Energy Contract DE-AC03-76SF00098 and by the Office of Naval Research under Contract N00014-95-F-0099.

PY - 1996/12

Y1 - 1996/12

N2 - Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.

AB - Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.

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Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules

Abstract

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