TY - JOUR
T1 - Dual imaging ofarterial walls
T2 - Diagnostic and Therapeutic Cardiovascular Interventions III 1993
AU - Pope, Karl
AU - Warren, Steve
AU - Yazdi, Youseph
AU - Johnston, Alfred
AU - Davis, Michael
AU - Kortum, Rebecca Richards
N1 - Funding Information:
The authors wish to acknowledge the contributions of Drs. Axe! Brisken and Yue-Teh Jang of Cardiovascular Interventional Systems in the design of the combined ultrasound/spectroscopy catheter. Financial support for this project was provided by a grant from the National Science Foundation, #BCS-9157202.
Publisher Copyright:
© 1993 SPIE. All rights reserved.
PY - 1993/6/23
Y1 - 1993/6/23
N2 - This paper describes a combined ultrasonic and spectroscopic system for imaging both the structure and chemical composition of atherosclerotic plaque. Using this system, ultrasound pulse echo distance estimations can be used to accurately compensate detected tissue fluorescence intensities for a wide range of tissue-detector separations, D. Compensation is achieved using an empirical model, wherein fluorescence intensity decreases as lID" with n=1.1 for tissue detector separations from 2.5 to 5 mm and 1.4 for separations of 5 to 15 mm. This behavior indicates that fluorescence exiting the tissue surface is not isotropic.
AB - This paper describes a combined ultrasonic and spectroscopic system for imaging both the structure and chemical composition of atherosclerotic plaque. Using this system, ultrasound pulse echo distance estimations can be used to accurately compensate detected tissue fluorescence intensities for a wide range of tissue-detector separations, D. Compensation is achieved using an empirical model, wherein fluorescence intensity decreases as lID" with n=1.1 for tissue detector separations from 2.5 to 5 mm and 1.4 for separations of 5 to 15 mm. This behavior indicates that fluorescence exiting the tissue surface is not isotropic.
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U2 - 10.1117/12.146589
DO - 10.1117/12.146589
M3 - Conference article
AN - SCOPUS:0013063099
SN - 0277-786X
VL - 1878
SP - 42
EP - 50
JO - Proceedings of SPIE - The International Society for Optical Engineering
JF - Proceedings of SPIE - The International Society for Optical Engineering
Y2 - 17 January 1993 through 22 January 1993
ER -