Dual frequency resonator for 1.2 GHz EPR/16.2 MHz NMR co-imaging

Sergey Petryakov, Alexandre Samouilov, Eric Kesselring, George L. Caia, Ziqi Sun, Jay L. Zweier

Research output: Contribution to journalArticle

Abstract

The development of a dual frequency resonator that enables both EPR and proton NMR imaging within the same resonator, magnet and gradient system is described. A novel design allows the same resonator to perform both EPR and proton NMR operation without moving resonator cables or switches. The resonator is capable of working at frequencies of 16.18 MHz for proton NMR and 1.2 GHz for EPR and is optimized for isolated rat heart experiments, measuring 22 mm in inner diameter and 19 mm in length. In EPR mode, the resonator functions as a one-loop-two gap resonator, electrically coupled through a half wavelength inverter. In NMR mode, it functions a single turn coil. Using the same loop for both modalities maximizes filling factor at both frequencies. Placing the tuning and switching controls away from the resonator prevents any inadvertent movement that would cause errors of EPR and NMR co-imaging registration. The resonator enabled good quality EPR and proton MRI of isolated rat hearts with precise registration.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Magnetic Resonance
Volume205
Issue number1
DOIs
StatePublished - Jul 2010
Externally publishedYes

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Keywords

  • Co-imaging
  • EPR
  • MRI
  • Resonator

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Biochemistry
  • Biophysics
  • Condensed Matter Physics

Cite this

Petryakov, S., Samouilov, A., Kesselring, E., Caia, G. L., Sun, Z., & Zweier, J. L. (2010). Dual frequency resonator for 1.2 GHz EPR/16.2 MHz NMR co-imaging. Journal of Magnetic Resonance, 205(1), 1-8. https://doi.org/10.1016/j.jmr.2010.02.020