DSM-5 latent classes of alcohol users in a population-based sample: Results from the São Paulo Megacity Mental Health Survey, Brazil

João Mauricio Castaldelli-Maia, Camila M. Silveira, Erica R. Siu, Yuan Pang Wang, Igor A. Milhorança, Clóvis Alexandrino-Silva, Guilherme Borges, Maria C. Viana, Arthur G. Andrade, Laura H. Andrade, Silvia S. Martins

Research output: Contribution to journalArticle

Abstract

Background: We aimed to identify different categorical phenotypes based upon the DSM-V criteria of alcohol use disorders (AUD) among alcohol users who had at least one drink per week in the past year (n= 948). Methods: Data are from the São Paulo Megacity Mental Health Survey collected in 2005-2007, as part of the World Mental Health Survey Initiative. A latent class analysis of the 11 DSM-5-AUD criteria was performed using Mplus, taking into account complex survey design features. Weighted logistic regression models were used to examine demographic correlates of the DSM-5-AUD latent classes. Results: The best latent-class model was a three-class model. We found a "non-symptomatic class" (69.7%), a "use in larger amounts class" (23.2%), defined by high probability (>70%) of the "use in larger amounts" criterion only, and a "high-moderate symptomatic class" (7.1%), defined by high-moderate probability of all the 11 AUD criteria. Compared to those in the non-symptomatic class, individuals in the "high-moderate symptomatic class" were more likely to have been married, have lower educational attainment and to be unemployed or in non-regular/informal employment. Those on the "use in larger amounts class" were more likely to have been married or never married. Conclusion: The two symptomatic classes clearly represented the dimensionality of the new proposed AUD criteria, and could be more specifically targeted by different prevention or treatment strategies. DSM-5-AUD has the advantage of shedding light on risky drinkers included in the "use in larger amounts class", allowing for preventive interventions, which will reach a large number of individuals.

Original languageEnglish (US)
Pages (from-to)92-99
Number of pages8
JournalDrug and alcohol dependence
Volume136
Issue number1
DOIs
StatePublished - Mar 1 2014

Keywords

  • Alcohol use disorders (AUD)
  • Brazil
  • DSM-5 criteria
  • Latent class analysis
  • São Paulo

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)

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    Castaldelli-Maia, J. M., Silveira, C. M., Siu, E. R., Wang, Y. P., Milhorança, I. A., Alexandrino-Silva, C., Borges, G., Viana, M. C., Andrade, A. G., Andrade, L. H., & Martins, S. S. (2014). DSM-5 latent classes of alcohol users in a population-based sample: Results from the São Paulo Megacity Mental Health Survey, Brazil. Drug and alcohol dependence, 136(1), 92-99. https://doi.org/10.1016/j.drugalcdep.2013.12.012