TY - JOUR
T1 - DSM-5 field trials in the United States and Canada, part I
T2 - Study design, sampling strategy, implementation, and analytic approaches
AU - Clarke, Diana E.
AU - Narrow, William E.
AU - Regier, Darrel A.
AU - Kuramoto, Janet
AU - Kupfer, David J.
AU - Kuhl, Emily A.
AU - Greiner, Lisa
AU - Kraemer, Helena C.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Objective: This article discusses the design, sampling strategy, implementation, and data analytic processes of the DSM-5 Field Trials. Method: The DSM-5 Field Trials were conducted by using a test-retest reliability design with a strati fied sampling approach across six adult and four pediatric sites in the United States and one adult site in Canada. A strati fied random sampling approach was used to enhance precision in the estimation of the reliability coefficients. A web-based research electronic data capture system was used for simultaneous data collection from patients and clinicians across sites and for centralized data management. Weighted descriptive analyses, intraclass kappa and intraclass correlation coefficients for stratified samples, and receiver operating curves were computed. The DSM-5 Field Trials capitalized on advances since DSM-III and DSM-IV in statistical measures of reliability (i.e., intraclass kappa for stratified samples) and other recently developed measures to determine confidence intervals around kappa estimates. Results: Diagnostic interviews using DSM-5 criteria were conducted by 279 clinicians of varied disciplines who received training comparable to what would be available to any clinician after publication of DSM-5. Overall, 2,246 patients with various diagnoses and levels of comorbiditywere enrolled, of which over 86% were seen for two diagnostic interviews. A range of reliability coefficients were observed for the categorical diagnoses and dimensional measures. Conclusions: Multisite field trials and training comparable to what would be available to any clinician after publication of DSM-5 provided "real-world" testing of DSM-5 proposed diagnoses.
AB - Objective: This article discusses the design, sampling strategy, implementation, and data analytic processes of the DSM-5 Field Trials. Method: The DSM-5 Field Trials were conducted by using a test-retest reliability design with a strati fied sampling approach across six adult and four pediatric sites in the United States and one adult site in Canada. A strati fied random sampling approach was used to enhance precision in the estimation of the reliability coefficients. A web-based research electronic data capture system was used for simultaneous data collection from patients and clinicians across sites and for centralized data management. Weighted descriptive analyses, intraclass kappa and intraclass correlation coefficients for stratified samples, and receiver operating curves were computed. The DSM-5 Field Trials capitalized on advances since DSM-III and DSM-IV in statistical measures of reliability (i.e., intraclass kappa for stratified samples) and other recently developed measures to determine confidence intervals around kappa estimates. Results: Diagnostic interviews using DSM-5 criteria were conducted by 279 clinicians of varied disciplines who received training comparable to what would be available to any clinician after publication of DSM-5. Overall, 2,246 patients with various diagnoses and levels of comorbiditywere enrolled, of which over 86% were seen for two diagnostic interviews. A range of reliability coefficients were observed for the categorical diagnoses and dimensional measures. Conclusions: Multisite field trials and training comparable to what would be available to any clinician after publication of DSM-5 provided "real-world" testing of DSM-5 proposed diagnoses.
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U2 - 10.1176/appi.ajp.2012.12070998
DO - 10.1176/appi.ajp.2012.12070998
M3 - Article
C2 - 23111546
AN - SCOPUS:84872056449
SN - 0002-953X
VL - 170
SP - 43
EP - 58
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
IS - 1
ER -