Drugs producing anesthesia and neuromuscular blocking

Research output: Chapter in Book/Report/Conference proceedingChapter


• Anesthesia is a loss of feeling or sensation. • Balanced anesthesia is a combination of anesthetic agents used to decrease the depth of anesthesia and keep the patient safe. • Anesthetic agents are divided into inhaled and intravenous agents. • Isofl urane (Forane) is a halogenated inhaled anesthetic. Nursing management of patients recovering from isofl urane anesthesia includes carefully monitoring residual CNS depression, manifested as respiratory depression. • Nitrous oxide is an infl ammable gas used to increase the effectiveness of halogenated agents without severely depressing the depth of coma. • Propofol (Diprivan) is the prototype intravenous anesthetic. It has a quick onset and short duration of action. • Ketamine (Ketalar) causes dissociative anesthesia. • Local anesthetics such as lidocaine produce local or regional anesthesia by blocking nerve conduction. They are used to facilitate various types of procedures. • Nondepolarizing NMJ blockers, such as tubocurarine, prevent nerve impulses from exciting muscle; paralysis ensues because the muscle is unable to respond. • Depolarizing NMJ blockers, such as succinylcholine, cause muscle paralysis by overexcitement (depolarization) and subsequent exhaustion of the muscle. • The NMJ blockers are primarily used as adjuncts to general anesthesia, to facilitate endotracheal intubation, or to facilitate mechanical ventilation.

Original languageEnglish (US)
Title of host publicationDrug Therapy in Nursing
PublisherWolters Kluwer Health Adis (ESP)
Number of pages25
ISBN (Electronic)9781469819174
ISBN (Print)9781451187663
StatePublished - Nov 7 2012

ASJC Scopus subject areas

  • Nursing(all)


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