Abstract
A millennium, a century, even a decade is a long time-frame for speculation about anything. Advances in biomedical research in the last few decades have been so extraordinary and escalating at an ever-accelerating pace that any prophecy is a risky proposition. However, it is possible to divine the big, unanswered questions and envisage ways in which they might reasonably be approached in the next few decades, a task which I will try to essay. So many drugs treat so many different medical conditions that a detailed and comprehensive coverage would probably be tiresome. Instead, I will address certain broad themes and diseases that offer both immense challenges and great potential for advances. Rather than review detailed experimental issues, I will confine myself to the 'big picture' issues, providing examples of specific research only in a few instances drawing largely from areas I know best.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1985-1994 |
| Number of pages | 10 |
| Journal | Philosophical Transactions of the Royal Society B: Biological Sciences |
| Volume | 354 |
| Issue number | 1392 |
| DOIs | |
| State | Published - Dec 29 1999 |
Keywords
- Antidepressants
- Cocaine
- Neuroleptics
- Nitric oxide
- Poly(ADP-ribose) polymerase
- Schizophrenia
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)