TY - JOUR
T1 - Drug resistant TB spine in a two year old child
T2 - A case report
AU - Giridharan, Prathiksha
AU - Selladurai, Elilarasi
AU - Balaji, Sarath
AU - Pramila, Snegha Karunakaran
AU - V, Arunagirinathan
AU - Shanmugam, Sivakumar
AU - Hissar, Syed
AU - Natrajan, Mohan
AU - Dooley, Kelly E.
AU - Daniel, Bella Devaleenal
N1 - Funding Information:
This was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development , United States ( R01HD074944 ).
Publisher Copyright:
© 2019 Tuberculosis Association of India
PY - 2020/7
Y1 - 2020/7
N2 - Spinal tuberculosis (TB) is a disease of high morbidity that is associated with deformity and neurological sequelae, especially in growing children. Children diagnosed with spinal TB need to be monitored closely for clinical improvements. Previous history of antituberculous therapy (ATT), poor adherence to previous ATT, contact with persons having known drug-resistant (DR) TB, or clinical worsening despite regular ATT are strong indicators for the diagnosis of DR TB of the spine. We report a case of spinal DRTB in a two year old child with no previous history of ATT and contact with a person on irregular treatment for drug sensitive TB that did not show regression of the spinal lesions despite standard ATT.
AB - Spinal tuberculosis (TB) is a disease of high morbidity that is associated with deformity and neurological sequelae, especially in growing children. Children diagnosed with spinal TB need to be monitored closely for clinical improvements. Previous history of antituberculous therapy (ATT), poor adherence to previous ATT, contact with persons having known drug-resistant (DR) TB, or clinical worsening despite regular ATT are strong indicators for the diagnosis of DR TB of the spine. We report a case of spinal DRTB in a two year old child with no previous history of ATT and contact with a person on irregular treatment for drug sensitive TB that did not show regression of the spinal lesions despite standard ATT.
KW - Children
KW - Drug resistant TB
KW - TB spine
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U2 - 10.1016/j.ijtb.2019.09.007
DO - 10.1016/j.ijtb.2019.09.007
M3 - Article
C2 - 32825872
AN - SCOPUS:85073955848
SN - 0019-5707
VL - 67
SP - 374
EP - 377
JO - Indian Journal of Tuberculosis
JF - Indian Journal of Tuberculosis
IS - 3
ER -