Drug-Induced Hypertension

Matthew C. Foy, Joban Vaishnav, C John Sperati

Research output: Contribution to journalReview article

Abstract

Untoward side effects of pharmaceuticals can result in considerable morbidity and expense to the health care system. There is likely a sizable fraction of the hypertensive population with disease either induced or exacerbated by polypharmacy. The elevation of blood pressure in drug-induced hypertension occurs through a variety of mechanisms, most notably, sodium and fluid retention, activation of the renin-angiotensin-aldosterone system, alteration of vascular tone, or a combination of these pathways. Recognition of common medications causing drug-induced hypertension is important to effectively control blood pressure. The epidemiology, pathophysiology, and management of these agents are discussed.

Original languageEnglish (US)
JournalEndocrinology and metabolism clinics of North America
DOIs
StateAccepted/In press - Jan 1 2019

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Blood Pressure
Hypertension
Polypharmacy
Renin-Angiotensin System
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations
Blood Vessels
Epidemiology
Sodium
Morbidity
Delivery of Health Care
Population

Keywords

  • Drug-induced hypertension
  • Polypharmacy
  • Secondary hypertension

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Drug-Induced Hypertension. / Foy, Matthew C.; Vaishnav, Joban; Sperati, C John.

In: Endocrinology and metabolism clinics of North America, 01.01.2019.

Research output: Contribution to journalReview article

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