Drug delivery

An integrated clinical and engineering approach

Yitzhak Rosen, Pablo Gurman, Noel M. Elman

Research output: Book/ReportBook

Abstract

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

Original languageEnglish (US)
PublisherCRC Press
Number of pages602
ISBN (Electronic)9781466565951
ISBN (Print)9781466565944
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Fingerprint

Biomedical Engineering
Pharmaceutical Preparations
Micro-Electrical-Mechanical Systems
Drug Compounding
Hydrogels
Thrombophilia
Nanostructures
Biocompatible Materials
Gynecology
Autoimmune Diseases
Obstetrics
Communicable Diseases
Heart Diseases
Neoplasms
Stem Cells
Pharmacokinetics
Clinical Trials
Insulin
Lipids
Equipment and Supplies

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Drug delivery : An integrated clinical and engineering approach. / Rosen, Yitzhak; Gurman, Pablo; Elman, Noel M.

CRC Press, 2017. 602 p.

Research output: Book/ReportBook

Rosen, Yitzhak ; Gurman, Pablo ; Elman, Noel M. / Drug delivery : An integrated clinical and engineering approach. CRC Press, 2017. 602 p.
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