TY - JOUR
T1 - Drosophila laminin
T2 - Sequence of B2 subunit and expression of all three subunits during embryogenesis
AU - Montell, D. J.
AU - Goodman, C. S.
PY - 1989
Y1 - 1989
N2 - In a previous study, we described the cloning of the genes encoding the three subunits of Drosophila laminin, a substrate adhesion molecule, and the cDNA sequence of the B1 subunit (Montell and Goodman, 1988). This analysis revealed the similarity of Drosophila laminin with the mouse and human complexes in subunit composition, domain structure, and amino acid sequence. In this paper, we report the deduced amino acid sequence of the B2 subunit. We then describe the expression and tissue distribution of the three subunits of laminin during Drosophila embryogenesis using both in situ hybridization and immunolocalization techniques, with particular emphasis on its expression in and around the developing nervous system.
AB - In a previous study, we described the cloning of the genes encoding the three subunits of Drosophila laminin, a substrate adhesion molecule, and the cDNA sequence of the B1 subunit (Montell and Goodman, 1988). This analysis revealed the similarity of Drosophila laminin with the mouse and human complexes in subunit composition, domain structure, and amino acid sequence. In this paper, we report the deduced amino acid sequence of the B2 subunit. We then describe the expression and tissue distribution of the three subunits of laminin during Drosophila embryogenesis using both in situ hybridization and immunolocalization techniques, with particular emphasis on its expression in and around the developing nervous system.
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U2 - 10.1083/jcb.109.5.2441
DO - 10.1083/jcb.109.5.2441
M3 - Article
C2 - 2808533
AN - SCOPUS:0024432466
SN - 0021-9525
VL - 109
SP - 2441
EP - 2453
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 5
ER -