Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed

Mikael Mazighi, Elena Meseguer, Julien Labreuche, Jean Michel Serfaty, Jean Pierre Laissy, Philippa C. Lavallée, Lucie Cabrejo, Céline Guidoux, Bertrand Lapergue, Isabelle F. Klein, Jean Marc Olivot, Aymeric Rouchaud, Jean Philippe Desilles, Elisabeth Schouman-Claeys, Pierre Amarenco

Research output: Contribution to journalArticle

Abstract

Background and Purpose-Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods-We analyzed data collected between April 2007 and May 2011 in our prospective clinical registry. All patients with acute ischemic stroke with National Institutes of Health Stroke Scale 10 at admission and an identification of arterial status before treatment were included. DR was defined as National Institutes of Health Stroke Scale ≤3 at 24 hours or a decrease of 10 points within 24 hours. Results-DR occurred in 75 of 255 patients with acute ischemic stroke (29.4%). Patients with persistent occlusion had a low DR rate (11.1%) than those with no documented occlusion (36.5%) and those with occlusion followed by recanalization (35.3%; both P

Original languageEnglish (US)
Pages (from-to)2998-3002
Number of pages5
JournalStroke
Volume43
Issue number11
DOIs
StatePublished - Nov 2012
Externally publishedYes

Keywords

  • acute stroke syndromes
  • dramatic recovery
  • recanalization
  • thrombolysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialized Nursing

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  • Cite this

    Mazighi, M., Meseguer, E., Labreuche, J., Serfaty, J. M., Laissy, J. P., Lavallée, P. C., Cabrejo, L., Guidoux, C., Lapergue, B., Klein, I. F., Olivot, J. M., Rouchaud, A., Desilles, J. P., Schouman-Claeys, E., & Amarenco, P. (2012). Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed. Stroke, 43(11), 2998-3002. https://doi.org/10.1161/STROKEAHA.112.658849