Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed

Mikael Mazighi; Elena Meseguer; Julien Labreuche; Jean Michel Serfaty; Jean Pierre Laissy; Philippa C. Lavallée; Lucie Cabrejo; Céline Guidoux; Bertrand Lapergue; Isabelle F. Klein; Jean Marc Olivot; Aymeric Rouchaud; Jean Philippe Desilles; Elisabeth Schouman-Claeys; Pierre Amarenco

doi:10.1161/STROKEAHA.112.658849

Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed

Mikael Mazighi, Elena Meseguer, Julien Labreuche, Jean Michel Serfaty, Jean Pierre Laissy, Philippa C. Lavallée, Lucie Cabrejo, Céline Guidoux, Bertrand Lapergue, Isabelle F. Klein, Jean Marc Olivot, Aymeric Rouchaud, Jean Philippe Desilles, Elisabeth Schouman-Claeys, Pierre Amarenco

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Background and Purpose-Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods-We analyzed data collected between April 2007 and May 2011 in our prospective clinical registry. All patients with acute ischemic stroke with National Institutes of Health Stroke Scale 10 at admission and an identification of arterial status before treatment were included. DR was defined as National Institutes of Health Stroke Scale ≤3 at 24 hours or a decrease of 10 points within 24 hours. Results-DR occurred in 75 of 255 patients with acute ischemic stroke (29.4%). Patients with persistent occlusion had a low DR rate (11.1%) than those with no documented occlusion (36.5%) and those with occlusion followed by recanalization (35.3%; both P

Original language	English (US)
Pages (from-to)	2998-3002
Number of pages	5
Journal	Stroke
Volume	43
Issue number	11
DOIs	https://doi.org/10.1161/STROKEAHA.112.658849
State	Published - Nov 2012
Externally published	Yes

Keywords

acute stroke syndromes
dramatic recovery
recanalization
thrombolysis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Clinical Neurology
Advanced and Specialized Nursing

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10.1161/STROKEAHA.112.658849

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Mazighi, M., Meseguer, E., Labreuche, J., Serfaty, J. M., Laissy, J. P., Lavallée, P. C., Cabrejo, L., Guidoux, C., Lapergue, B., Klein, I. F., Olivot, J. M., Rouchaud, A., Desilles, J. P., Schouman-Claeys, E., & Amarenco, P. (2012). Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed. Stroke, 43(11), 2998-3002. https://doi.org/10.1161/STROKEAHA.112.658849

Mazighi, M, Meseguer, E, Labreuche, J, Serfaty, JM, Laissy, JP, Lavallée, PC, Cabrejo, L, Guidoux, C, Lapergue, B, Klein, IF, Olivot, JM, Rouchaud, A, Desilles, JP, Schouman-Claeys, E & Amarenco, P 2012, 'Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed', Stroke, vol. 43, no. 11, pp. 2998-3002. https://doi.org/10.1161/STROKEAHA.112.658849

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abstract = "Background and Purpose-Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods-We analyzed data collected between April 2007 and May 2011 in our prospective clinical registry. All patients with acute ischemic stroke with National Institutes of Health Stroke Scale 10 at admission and an identification of arterial status before treatment were included. DR was defined as National Institutes of Health Stroke Scale ≤3 at 24 hours or a decrease of 10 points within 24 hours. Results-DR occurred in 75 of 255 patients with acute ischemic stroke (29.4%). Patients with persistent occlusion had a low DR rate (11.1%) than those with no documented occlusion (36.5%) and those with occlusion followed by recanalization (35.3%; both P",

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AU - Laissy, Jean Pierre

AU - Lavallée, Philippa C.

AU - Cabrejo, Lucie

AU - Guidoux, Céline

AU - Lapergue, Bertrand

AU - Klein, Isabelle F.

AU - Olivot, Jean Marc

AU - Rouchaud, Aymeric

AU - Desilles, Jean Philippe

AU - Schouman-Claeys, Elisabeth

AU - Amarenco, Pierre

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N2 - Background and Purpose-Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods-We analyzed data collected between April 2007 and May 2011 in our prospective clinical registry. All patients with acute ischemic stroke with National Institutes of Health Stroke Scale 10 at admission and an identification of arterial status before treatment were included. DR was defined as National Institutes of Health Stroke Scale ≤3 at 24 hours or a decrease of 10 points within 24 hours. Results-DR occurred in 75 of 255 patients with acute ischemic stroke (29.4%). Patients with persistent occlusion had a low DR rate (11.1%) than those with no documented occlusion (36.5%) and those with occlusion followed by recanalization (35.3%; both P

AB - Background and Purpose-Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods-We analyzed data collected between April 2007 and May 2011 in our prospective clinical registry. All patients with acute ischemic stroke with National Institutes of Health Stroke Scale 10 at admission and an identification of arterial status before treatment were included. DR was defined as National Institutes of Health Stroke Scale ≤3 at 24 hours or a decrease of 10 points within 24 hours. Results-DR occurred in 75 of 255 patients with acute ischemic stroke (29.4%). Patients with persistent occlusion had a low DR rate (11.1%) than those with no documented occlusion (36.5%) and those with occlusion followed by recanalization (35.3%; both P

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Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed

Abstract

Keywords

ASJC Scopus subject areas

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