Draft genome sequence of Mycobacterium tuberculosis strain E186hv of Beijing B0/W lineage with reduced virulence

K. V. Shur, K. M. Klimina, N. V. Zakharevich, D. A. Maslov, O. B. Bekker, M. V. Zaychikova, E. Y. Kamaev, M. A. Kravchenko, S. N. Skornyakov, Y. Zhang, V. N. Danilenko

Research output: Contribution to journalArticlepeer-review

Abstract

We report a draft genome sequence of Mycobacterium tuberculosis strain E186hv, belonging to the Beijing B0/W lineage and isolated from a patient from Kurgan, Russia. This clinical isolate showed a reduced virulence phenotype unusual for this lineage and resistance to isoniazid, rifampin, ethambutol, pyrazinamide, and ofloxacin. We analyzed single nucleotide polymorphisms (SNPs) associated with virulence.

Original languageEnglish (US)
Article numbere00403-15
JournalGenome Announcements
Volume3
Issue number3
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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