Down's syndrome and Alzheimer's disease: Towards secondary prevention

Seth Ness, Michael Rafii, Paul Aisen, Michael Krams, Wayne Silverman, Husseini Manji

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


A public-private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions.

Original languageEnglish (US)
Pages (from-to)655-656
Number of pages2
JournalNature Reviews Drug Discovery
Issue number9
StatePublished - Sep 2012

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery


Dive into the research topics of 'Down's syndrome and Alzheimer's disease: Towards secondary prevention'. Together they form a unique fingerprint.

Cite this