Dose-intensive approaches to ovarian cancer.

N. Lambrou, E. L. Trimble

Research output: Contribution to journalReview articlepeer-review


Increasing the total dose or the dose intensity of platinum does not improve survival in women with ovarian cancer. High-dose chemotherapy with hematologic support has not been shown to be more effective than standard-dose chemotherapy. Regional dose intensity, through intraperitoneal chemotherapy, may have a role in the treatment of advanced ovarian cancer. Further studies are needed to identify the optimal combination of agents, in addition to a platinum and a taxane, to be used in primary therapy for ovarian cancer.

Original languageEnglish (US)
Pages (from-to)54-58
Number of pages5
JournalCurrent oncology reports
Issue number1
StatePublished - Sep 1999

ASJC Scopus subject areas

  • Oncology


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