Dopamine transporter imaging with novel, selective cocaine analogs

U. Scheffel; R. F. Dannals; D. F. Wong; F. Yokoi; F. I. Carroll; M. J. Kuhar

doi:10.1097/00001756-199211000-00005

Dopamine transporter imaging with novel, selective cocaine analogs

U. Scheffel, R. F. Dannals, D. F. Wong, F. Yokoi, F. I. Carroll, M. J. Kuhar

School of Medicine

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

Original language	English (US)
Pages (from-to)	969-972
Number of pages	4
Journal	Neuroreport
Volume	3
Issue number	11
DOIs	https://doi.org/10.1097/00001756-199211000-00005
State	Published - Nov 1992

Keywords

Cocaine
Dopamine transporter
Dopamine uptake
RTI-121
RTI-122
RTI-55
SPECT imaging

ASJC Scopus subject areas

General Neuroscience

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10.1097/00001756-199211000-00005

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title = "Dopamine transporter imaging with novel, selective cocaine analogs",

abstract = "RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.",

keywords = "Cocaine, Dopamine transporter, Dopamine uptake, RTI-121, RTI-122, RTI-55, SPECT imaging",

author = "U. Scheffel and Dannals, {R. F.} and Wong, {D. F.} and F. Yokoi and Carroll, {F. I.} and Kuhar, {M. J.}",

year = "1992",

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AU - Scheffel, U.

AU - Dannals, R. F.

AU - Wong, D. F.

AU - Yokoi, F.

AU - Carroll, F. I.

AU - Kuhar, M. J.

PY - 1992/11

Y1 - 1992/11

N2 - RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

AB - RTI-121 and RTI-122 are 3p-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [,23I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

KW - Cocaine

KW - Dopamine transporter

KW - Dopamine uptake

KW - RTI-121

KW - RTI-122

KW - RTI-55

KW - SPECT imaging

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ER -

Dopamine transporter imaging with novel, selective cocaine analogs

Abstract

Keywords

ASJC Scopus subject areas

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