Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta-analysis of the past 10 years

Brian S. Appleby, Kristin K. Appleby, Peter V. Rabins

Research output: Contribution to journalArticlepeer-review

Abstract

It is not clear whether differences in symptom presentation vary by age or etiological subtype in Creutzfeldt-Jakob disease. A PubMed search was conducted using the keyword "Creutzfeldt-Jakob" and results within the last 10 years were sorted by the English language. We found that certain characteristics, such as affective illness (28.8%), present more commonly in younger patients irrespective of disease type. Young age of onset predicts presenting symptoms of affective illness, sleep disturbance, and poor concentration, as well as certain neurological symptoms, including cerebellar/gait disturbance, visual/oculomotor disturbance, sensory disorder, vertigo/dizziness, and headache.

Original languageEnglish (US)
Pages (from-to)428-435
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume19
Issue number4
DOIs
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

Fingerprint

Dive into the research topics of 'Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta-analysis of the past 10 years'. Together they form a unique fingerprint.

Cite this