Does preeclamptic pregnancy increase fetal-maternal hemorrhage?

C. D. Hsu, K. Smith, S. F. Hong, T. R.B. Johnson, Y. Gollin, D. W. Chan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Since pathologic changes of the placenta have been found in preeclamptic pregnancies, a relationship between fetal-maternal hemorrhage and preeclampsia was investigated. Sixty-two women with singleton pregnancies in the third trimester were studied. Thirty-one of these women with preeclampsia were matched with 31 normotensive healthy pregnant women. Maternal serum levels of α-fetoprotein (MSAFP) and Kleihauer-Betke (KB) test were determined to reflect the degree of fetal-maternal hemorrhage. There were no significant differences in MSAFP levels, MSAFP to creatinine ratio, or the appearance of fetal cells as measured by the KB test between preeclamptic pregnancies and matched controls. Our data do not suggest that fetal-maternal hemorrhage is increased in pregnant women with preeclampsia.

Original languageEnglish (US)
Pages (from-to)205-207
Number of pages3
JournalAmerican journal of perinatology
Issue number3
StatePublished - Jan 1 1995
Externally publishedYes


  • Preeclampsia
  • fetal-maternal hemorrhage
  • pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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