Does phase 1 trial enrollment preclude quality end-of-life care? Phase 1 trial enrollment and end-of-life care characteristics in children with cancer

Deena R. Levine, Liza Marie Johnson, Belinda N. Mandrell, Jie Yang, Nancy K. West, Pamela S. Hinds, Justin N. Baker

Research output: Contribution to journalArticle

Abstract

Background End-of-life care (EOLC) discussions and treatment-related decisions, including phase 1 trial enrollment, in patients with incurable disease are complex and can influence the quality of EOLC received. The current study was conducted in pediatric oncology patients to determine whether end-of-life characteristics differed between those who were and were not enrolled in a phase 1 trial. Methods The authors reviewed the medical records of 380 pediatric oncology patients (aged

Original languageEnglish (US)
Pages (from-to)1508-1512
Number of pages5
JournalCancer
Volume121
Issue number9
DOIs
StatePublished - May 1 2015
Externally publishedYes

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Terminal Care
Quality of Life
Pediatrics
Neoplasms
Medical Records
Therapeutics

Keywords

  • end-of-life care
  • oncology
  • pediatric oncology
  • phase 1 clinical trials

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

Cite this

Levine, D. R., Johnson, L. M., Mandrell, B. N., Yang, J., West, N. K., Hinds, P. S., & Baker, J. N. (2015). Does phase 1 trial enrollment preclude quality end-of-life care? Phase 1 trial enrollment and end-of-life care characteristics in children with cancer. Cancer, 121(9), 1508-1512. https://doi.org/10.1002/cncr.29230

Does phase 1 trial enrollment preclude quality end-of-life care? Phase 1 trial enrollment and end-of-life care characteristics in children with cancer. / Levine, Deena R.; Johnson, Liza Marie; Mandrell, Belinda N.; Yang, Jie; West, Nancy K.; Hinds, Pamela S.; Baker, Justin N.

In: Cancer, Vol. 121, No. 9, 01.05.2015, p. 1508-1512.

Research output: Contribution to journalArticle

Levine, Deena R. ; Johnson, Liza Marie ; Mandrell, Belinda N. ; Yang, Jie ; West, Nancy K. ; Hinds, Pamela S. ; Baker, Justin N. / Does phase 1 trial enrollment preclude quality end-of-life care? Phase 1 trial enrollment and end-of-life care characteristics in children with cancer. In: Cancer. 2015 ; Vol. 121, No. 9. pp. 1508-1512.
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