Does multimodal treatment of ADHD decrease other diagnoses?

Lily Hechtman, Joy Etcovitch, Robert Platt, L. Eugene Arnold, Howard B. Abikoff, Jeffery H. Newcorn, Betsy Hoza, Stephen P. Hinshaw, Helena C. Kraemer, Karen Wells, Keith Conners, Glen Elliott, Laurence L. Greenhill, Peter S. Jensen, John S. March, Brooke Molina, William E. Pelham, Joanne B. Severe, James M. Swanson, Benedetto VitielloTimothy Wigal

Research output: Contribution to journalArticle

Abstract

Comorbid conditions in children with attention deficit hyperactivity disorder (ADHD) are frequent and can affect treatment response and life course. From the multimodal treatment study of ADHD (MTA), we examined the persistence or development of conditions other than ADHD, e.g. oppositional defiant disorder (ODD), conduct disorder (CD), anxiety, depression, and learning disorder (LD) in 576 children, age 7-9 years, diagnosed rigorously with ADHD, who were randomly assigned to four different treatments for 14 months. The treatment groups were medication management alone (MedMgt), behavioral treatment alone (Beh), the combination (Comb), and community comparison routine care (CC). For the sample as a whole, we found significant decreases from baseline to 14 months in diagnoses of ODD, CD, and anxiety disorder but not LD or mood disorder. The CC group developed significantly more new ODD and retained more baseline ODD than the Comb or MedMgt groups. There were no significant treatment group differences for specific other conditions. Only the Comb group was significantly better than the CC group in reducing total number of disorders and impairment at 14 months in subjects with multiple conditions at baseline. Well-titrated and monitored stimulant medication can decrease ODD and possibly prevent future CD. Combined treatment may be required for the most disturbed children with ADHD who have multiple disorders and severe impairment.

Original languageEnglish (US)
Pages (from-to)273-282
Number of pages10
JournalClinical Neuroscience Research
Volume5
Issue number5-6
DOIs
StatePublished - Dec 2005
Externally publishedYes

Fingerprint

Combined Modality Therapy
Attention Deficit and Disruptive Behavior Disorders
Attention Deficit Disorder with Hyperactivity
Conduct Disorder
Learning Disorders
Anxiety Disorders
Therapeutics
Mood Disorders
Depression

Keywords

  • ADHD
  • Behavioral treatment
  • Comorbidity
  • Multimodal treatment
  • Outcome

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Neurology
  • Neuropsychology and Physiological Psychology

Cite this

Hechtman, L., Etcovitch, J., Platt, R., Arnold, L. E., Abikoff, H. B., Newcorn, J. H., ... Wigal, T. (2005). Does multimodal treatment of ADHD decrease other diagnoses? Clinical Neuroscience Research, 5(5-6), 273-282. https://doi.org/10.1016/j.cnr.2005.09.007

Does multimodal treatment of ADHD decrease other diagnoses? / Hechtman, Lily; Etcovitch, Joy; Platt, Robert; Arnold, L. Eugene; Abikoff, Howard B.; Newcorn, Jeffery H.; Hoza, Betsy; Hinshaw, Stephen P.; Kraemer, Helena C.; Wells, Karen; Conners, Keith; Elliott, Glen; Greenhill, Laurence L.; Jensen, Peter S.; March, John S.; Molina, Brooke; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Vitiello, Benedetto; Wigal, Timothy.

In: Clinical Neuroscience Research, Vol. 5, No. 5-6, 12.2005, p. 273-282.

Research output: Contribution to journalArticle

Hechtman, L, Etcovitch, J, Platt, R, Arnold, LE, Abikoff, HB, Newcorn, JH, Hoza, B, Hinshaw, SP, Kraemer, HC, Wells, K, Conners, K, Elliott, G, Greenhill, LL, Jensen, PS, March, JS, Molina, B, Pelham, WE, Severe, JB, Swanson, JM, Vitiello, B & Wigal, T 2005, 'Does multimodal treatment of ADHD decrease other diagnoses?', Clinical Neuroscience Research, vol. 5, no. 5-6, pp. 273-282. https://doi.org/10.1016/j.cnr.2005.09.007
Hechtman L, Etcovitch J, Platt R, Arnold LE, Abikoff HB, Newcorn JH et al. Does multimodal treatment of ADHD decrease other diagnoses? Clinical Neuroscience Research. 2005 Dec;5(5-6):273-282. https://doi.org/10.1016/j.cnr.2005.09.007
Hechtman, Lily ; Etcovitch, Joy ; Platt, Robert ; Arnold, L. Eugene ; Abikoff, Howard B. ; Newcorn, Jeffery H. ; Hoza, Betsy ; Hinshaw, Stephen P. ; Kraemer, Helena C. ; Wells, Karen ; Conners, Keith ; Elliott, Glen ; Greenhill, Laurence L. ; Jensen, Peter S. ; March, John S. ; Molina, Brooke ; Pelham, William E. ; Severe, Joanne B. ; Swanson, James M. ; Vitiello, Benedetto ; Wigal, Timothy. / Does multimodal treatment of ADHD decrease other diagnoses?. In: Clinical Neuroscience Research. 2005 ; Vol. 5, No. 5-6. pp. 273-282.
@article{ff19b6fd110340e8b801effb5342e1e1,
title = "Does multimodal treatment of ADHD decrease other diagnoses?",
abstract = "Comorbid conditions in children with attention deficit hyperactivity disorder (ADHD) are frequent and can affect treatment response and life course. From the multimodal treatment study of ADHD (MTA), we examined the persistence or development of conditions other than ADHD, e.g. oppositional defiant disorder (ODD), conduct disorder (CD), anxiety, depression, and learning disorder (LD) in 576 children, age 7-9 years, diagnosed rigorously with ADHD, who were randomly assigned to four different treatments for 14 months. The treatment groups were medication management alone (MedMgt), behavioral treatment alone (Beh), the combination (Comb), and community comparison routine care (CC). For the sample as a whole, we found significant decreases from baseline to 14 months in diagnoses of ODD, CD, and anxiety disorder but not LD or mood disorder. The CC group developed significantly more new ODD and retained more baseline ODD than the Comb or MedMgt groups. There were no significant treatment group differences for specific other conditions. Only the Comb group was significantly better than the CC group in reducing total number of disorders and impairment at 14 months in subjects with multiple conditions at baseline. Well-titrated and monitored stimulant medication can decrease ODD and possibly prevent future CD. Combined treatment may be required for the most disturbed children with ADHD who have multiple disorders and severe impairment.",
keywords = "ADHD, Behavioral treatment, Comorbidity, Multimodal treatment, Outcome",
author = "Lily Hechtman and Joy Etcovitch and Robert Platt and Arnold, {L. Eugene} and Abikoff, {Howard B.} and Newcorn, {Jeffery H.} and Betsy Hoza and Hinshaw, {Stephen P.} and Kraemer, {Helena C.} and Karen Wells and Keith Conners and Glen Elliott and Greenhill, {Laurence L.} and Jensen, {Peter S.} and March, {John S.} and Brooke Molina and Pelham, {William E.} and Severe, {Joanne B.} and Swanson, {James M.} and Benedetto Vitiello and Timothy Wigal",
year = "2005",
month = "12",
doi = "10.1016/j.cnr.2005.09.007",
language = "English (US)",
volume = "5",
pages = "273--282",
journal = "Clinical Neuroscience Research",
issn = "1566-2772",
publisher = "Elsevier BV",
number = "5-6",

}

TY - JOUR

T1 - Does multimodal treatment of ADHD decrease other diagnoses?

AU - Hechtman, Lily

AU - Etcovitch, Joy

AU - Platt, Robert

AU - Arnold, L. Eugene

AU - Abikoff, Howard B.

AU - Newcorn, Jeffery H.

AU - Hoza, Betsy

AU - Hinshaw, Stephen P.

AU - Kraemer, Helena C.

AU - Wells, Karen

AU - Conners, Keith

AU - Elliott, Glen

AU - Greenhill, Laurence L.

AU - Jensen, Peter S.

AU - March, John S.

AU - Molina, Brooke

AU - Pelham, William E.

AU - Severe, Joanne B.

AU - Swanson, James M.

AU - Vitiello, Benedetto

AU - Wigal, Timothy

PY - 2005/12

Y1 - 2005/12

N2 - Comorbid conditions in children with attention deficit hyperactivity disorder (ADHD) are frequent and can affect treatment response and life course. From the multimodal treatment study of ADHD (MTA), we examined the persistence or development of conditions other than ADHD, e.g. oppositional defiant disorder (ODD), conduct disorder (CD), anxiety, depression, and learning disorder (LD) in 576 children, age 7-9 years, diagnosed rigorously with ADHD, who were randomly assigned to four different treatments for 14 months. The treatment groups were medication management alone (MedMgt), behavioral treatment alone (Beh), the combination (Comb), and community comparison routine care (CC). For the sample as a whole, we found significant decreases from baseline to 14 months in diagnoses of ODD, CD, and anxiety disorder but not LD or mood disorder. The CC group developed significantly more new ODD and retained more baseline ODD than the Comb or MedMgt groups. There were no significant treatment group differences for specific other conditions. Only the Comb group was significantly better than the CC group in reducing total number of disorders and impairment at 14 months in subjects with multiple conditions at baseline. Well-titrated and monitored stimulant medication can decrease ODD and possibly prevent future CD. Combined treatment may be required for the most disturbed children with ADHD who have multiple disorders and severe impairment.

AB - Comorbid conditions in children with attention deficit hyperactivity disorder (ADHD) are frequent and can affect treatment response and life course. From the multimodal treatment study of ADHD (MTA), we examined the persistence or development of conditions other than ADHD, e.g. oppositional defiant disorder (ODD), conduct disorder (CD), anxiety, depression, and learning disorder (LD) in 576 children, age 7-9 years, diagnosed rigorously with ADHD, who were randomly assigned to four different treatments for 14 months. The treatment groups were medication management alone (MedMgt), behavioral treatment alone (Beh), the combination (Comb), and community comparison routine care (CC). For the sample as a whole, we found significant decreases from baseline to 14 months in diagnoses of ODD, CD, and anxiety disorder but not LD or mood disorder. The CC group developed significantly more new ODD and retained more baseline ODD than the Comb or MedMgt groups. There were no significant treatment group differences for specific other conditions. Only the Comb group was significantly better than the CC group in reducing total number of disorders and impairment at 14 months in subjects with multiple conditions at baseline. Well-titrated and monitored stimulant medication can decrease ODD and possibly prevent future CD. Combined treatment may be required for the most disturbed children with ADHD who have multiple disorders and severe impairment.

KW - ADHD

KW - Behavioral treatment

KW - Comorbidity

KW - Multimodal treatment

KW - Outcome

UR - http://www.scopus.com/inward/record.url?scp=29744454080&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=29744454080&partnerID=8YFLogxK

U2 - 10.1016/j.cnr.2005.09.007

DO - 10.1016/j.cnr.2005.09.007

M3 - Article

AN - SCOPUS:29744454080

VL - 5

SP - 273

EP - 282

JO - Clinical Neuroscience Research

JF - Clinical Neuroscience Research

SN - 1566-2772

IS - 5-6

ER -