Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

Jeremy S. Nel, Christopher K. Lippincott, Rebecca Berhanu, David C. Spencer, Ian M. Sanne, Prudence Ive

Research output: Contribution to journalArticlepeer-review

Abstract

We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.

Original languageEnglish (US)
Pages (from-to)1226-1228
Number of pages3
JournalClinical Infectious Diseases
Volume65
Issue number7
DOIs
StatePublished - Oct 1 2017

Keywords

  • Determine TB-LAM
  • lipoarabinomannan
  • nontuberculous mycobacteria
  • tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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