Does aspirin use make it harder to collect seizures during elective video-EEG telemetry?

Rachel M. Godfred, Mihir S. Parikh, Alan M. Haltiner, Lisa M. Caylor, Jehuda P. Sepkuty, Michael J. Doherty

Research output: Contribution to journalArticle

Abstract

Aspirin has shown promise as an anticonvulsant drug in animal models. Whether aspirin alters seizure frequency in humans remains unstudied. We retrospectively looked at adults with focal onset epilepsy who took aspirin daily while undergoing elective video-EEG monitoring and compared them with similar age- and sex-matched controls to see if seizure frequencies were different between those two populations. Significantly fewer seizures were seen on day two of monitoring for patients on aspirin therapies. Higher aspirin doses were correlated with fewer seizures collected during the monitoring stay. Further prospective study is needed to determine whether aspirin affects more robust seizure control.

Original languageEnglish (US)
Pages (from-to)115-117
Number of pages3
JournalEpilepsy and Behavior
Volume27
Issue number1
DOIs
StatePublished - Apr 2013
Externally publishedYes

Keywords

  • Anticonvulsant
  • Antiepileptic
  • Epilepsy
  • Inflammation
  • Ischemia
  • Therapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

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  • Cite this

    Godfred, R. M., Parikh, M. S., Haltiner, A. M., Caylor, L. M., Sepkuty, J. P., & Doherty, M. J. (2013). Does aspirin use make it harder to collect seizures during elective video-EEG telemetry? Epilepsy and Behavior, 27(1), 115-117. https://doi.org/10.1016/j.yebeh.2012.12.031