DNA methylation analysis in human cancer

Eileen O'Sullivan, Michael S Goggins

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages131-156
Number of pages26
Volume980
ISBN (Print)9781627032865
DOIs
StatePublished - 2013
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume980
ISSN (Print)10643745

Fingerprint

DNA Methylation
Neoplasms

Keywords

  • 5-Aza-deoxycytidine
  • 5-Hydroxymethylcytosine
  • 5-Methylcytosine
  • Bisulfite
  • CpG island
  • Methylation-specific PCR
  • Methylbinding protein

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Medicine(all)

Cite this

O'Sullivan, E., & Goggins, M. S. (2013). DNA methylation analysis in human cancer. In Methods in Molecular Biology (Vol. 980, pp. 131-156). (Methods in Molecular Biology; Vol. 980). Humana Press Inc.. https://doi.org/10.1007/978-1-62703-287-2_7

DNA methylation analysis in human cancer. / O'Sullivan, Eileen; Goggins, Michael S.

Methods in Molecular Biology. Vol. 980 Humana Press Inc., 2013. p. 131-156 (Methods in Molecular Biology; Vol. 980).

Research output: Chapter in Book/Report/Conference proceedingChapter

O'Sullivan, E & Goggins, MS 2013, DNA methylation analysis in human cancer. in Methods in Molecular Biology. vol. 980, Methods in Molecular Biology, vol. 980, Humana Press Inc., pp. 131-156. https://doi.org/10.1007/978-1-62703-287-2_7
O'Sullivan E, Goggins MS. DNA methylation analysis in human cancer. In Methods in Molecular Biology. Vol. 980. Humana Press Inc. 2013. p. 131-156. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-62703-287-2_7
O'Sullivan, Eileen ; Goggins, Michael S. / DNA methylation analysis in human cancer. Methods in Molecular Biology. Vol. 980 Humana Press Inc., 2013. pp. 131-156 (Methods in Molecular Biology).
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