DNA adducts as markers of exposure in hazardous waste workers.

M. A. McDiarmid, P. T. Strickland

Research output: Contribution to journalReview article

Abstract

The interaction of a chemical or physical agent with DNA, resulting in the formation of covalent adducts or other modifications, has been implicated in the carcinogenic process for certain classes of chemicals. Demonstration of modified DNA may be taken as evidence of the interaction of a genotoxic agent with DNA, which is the basis for this review of DNA adducts as markers of exposure in hazardous waste work.

Original languageEnglish (US)
Pages (from-to)49-58
Number of pages10
JournalOccupational medicine (Philadelphia, Pa.)
Volume5
Issue number1
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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