The interaction of a chemical or physical agent with DNA, resulting in the formation of covalent adducts or other modifications, has been implicated in the carcinogenic process for certain classes of chemicals. Demonstration of modified DNA may be taken as evidence of the interaction of a genotoxic agent with DNA, which is the basis for this review of DNA adducts as markers of exposure in hazardous waste work.
|Original language||English (US)|
|Number of pages||10|
|Journal||Occupational medicine (Philadelphia, Pa.)|
|State||Published - Jan 1 1990|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health