Divergence of primate ribosomal RNA genes as assayed by restriction enzyme analysis

Research output: Contribution to journalArticlepeer-review

Abstract

Primate ribosomal RNA (rRNA) genes have been compared by restriction endonuclease mapping. In all species examined, the restriction map of the reiterated ribosomal DNA is simple (within the limits of detection by hybridization with rRNA) and is consistent with a high degree of homogeneity among the repeats. Within a species, all members have similar rDNA restriction patterns. However, different species of primates have distinctly different rDNA restriction maps; even chimpanzee and man can be discerned by their rDNA restriction patterns. Possible mechanisms for maintenance of homogeneity of the rDNA repeats within a species, while allowing divergence among closely related species, are discussed.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalGene
Volume11
Issue number1-2
DOIs
StatePublished - Jan 1 1980

Keywords

  • Phylogeny
  • RNA-DNA hybridization
  • SDS
  • kbp
  • kilobase pairs
  • multigene families
  • sodium dodecyl sulfate

ASJC Scopus subject areas

  • Genetics

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