Diurnal temperature range is a risk factor for coronary heart disease death

Jingyan Cao, Yuexin Cheng, Ni Zhao, Weimin Song, Cheng Jiang, Renjie Chen, Haidong Kan

Research output: Contribution to journalArticle

Abstract

Background: Although the relation between day-to-day temperature change and coronary heart disease (CHD) mortality is well established, it is unknown whether temperature variation within 1 day, ie, diurnal temperature range (DTR), is an independent risk factor for acute CHD death. Methods: We used time-series and case-crossover approaches to assess the relation between DTR and daily CHD mortality between 2001 and 2004 in Shanghai, China. Specifically, we used exposures averaged over periods varying from 1 to 5 days to assess the effects of DTR on CHD mortality. We estimated the percent increase in the number of daily deaths related to CHD that were associated with DTR, after adjustment for daily meteorologic conditions (temperature and relative humidity) and levels of outdoor air pollutants. Results: Both time-series and case-crossover analyses showed that DTR was significantly associated with the number of daily deaths related to CHD. A 1 °C increase in 2-day lagged DTR corresponded to a 2.46% (95% CI, 1.76% to 3.16%) increase in CHD mortality on time-series analysis, a 3.21% (95% CI, 2.23% to 4.19%) increase on unidirectional case-crossover analysis, and a 2.13% (95% CI, 1.04% to 3.22%) increase on bidirectional casecrossover analysis. Conclusions: Our findings suggest that DTR is an independent risk factor for acute CHD death.

Original languageEnglish (US)
Pages (from-to)328-332
Number of pages5
JournalJournal of Epidemiology
Volume19
Issue number6
DOIs
StatePublished - Nov 2009
Externally publishedYes

Fingerprint

Coronary Disease
Temperature
Mortality
Air Pollutants
Humidity
China

Keywords

  • Case-crossover
  • Coronary heart disease
  • Diurnal temperature range
  • Mortality
  • Time-series

ASJC Scopus subject areas

  • Epidemiology
  • Medicine(all)

Cite this

Diurnal temperature range is a risk factor for coronary heart disease death. / Cao, Jingyan; Cheng, Yuexin; Zhao, Ni; Song, Weimin; Jiang, Cheng; Chen, Renjie; Kan, Haidong.

In: Journal of Epidemiology, Vol. 19, No. 6, 11.2009, p. 328-332.

Research output: Contribution to journalArticle

Cao, Jingyan ; Cheng, Yuexin ; Zhao, Ni ; Song, Weimin ; Jiang, Cheng ; Chen, Renjie ; Kan, Haidong. / Diurnal temperature range is a risk factor for coronary heart disease death. In: Journal of Epidemiology. 2009 ; Vol. 19, No. 6. pp. 328-332.
@article{71e087bf80ad4c699a869e1fb8ff48af,
title = "Diurnal temperature range is a risk factor for coronary heart disease death",
abstract = "Background: Although the relation between day-to-day temperature change and coronary heart disease (CHD) mortality is well established, it is unknown whether temperature variation within 1 day, ie, diurnal temperature range (DTR), is an independent risk factor for acute CHD death. Methods: We used time-series and case-crossover approaches to assess the relation between DTR and daily CHD mortality between 2001 and 2004 in Shanghai, China. Specifically, we used exposures averaged over periods varying from 1 to 5 days to assess the effects of DTR on CHD mortality. We estimated the percent increase in the number of daily deaths related to CHD that were associated with DTR, after adjustment for daily meteorologic conditions (temperature and relative humidity) and levels of outdoor air pollutants. Results: Both time-series and case-crossover analyses showed that DTR was significantly associated with the number of daily deaths related to CHD. A 1 °C increase in 2-day lagged DTR corresponded to a 2.46{\%} (95{\%} CI, 1.76{\%} to 3.16{\%}) increase in CHD mortality on time-series analysis, a 3.21{\%} (95{\%} CI, 2.23{\%} to 4.19{\%}) increase on unidirectional case-crossover analysis, and a 2.13{\%} (95{\%} CI, 1.04{\%} to 3.22{\%}) increase on bidirectional casecrossover analysis. Conclusions: Our findings suggest that DTR is an independent risk factor for acute CHD death.",
keywords = "Case-crossover, Coronary heart disease, Diurnal temperature range, Mortality, Time-series",
author = "Jingyan Cao and Yuexin Cheng and Ni Zhao and Weimin Song and Cheng Jiang and Renjie Chen and Haidong Kan",
year = "2009",
month = "11",
doi = "10.2188/jea.JE20080074",
language = "English (US)",
volume = "19",
pages = "328--332",
journal = "Journal of Epidemiology",
issn = "0917-5040",
publisher = "Japan Epidemiology Association",
number = "6",

}

TY - JOUR

T1 - Diurnal temperature range is a risk factor for coronary heart disease death

AU - Cao, Jingyan

AU - Cheng, Yuexin

AU - Zhao, Ni

AU - Song, Weimin

AU - Jiang, Cheng

AU - Chen, Renjie

AU - Kan, Haidong

PY - 2009/11

Y1 - 2009/11

N2 - Background: Although the relation between day-to-day temperature change and coronary heart disease (CHD) mortality is well established, it is unknown whether temperature variation within 1 day, ie, diurnal temperature range (DTR), is an independent risk factor for acute CHD death. Methods: We used time-series and case-crossover approaches to assess the relation between DTR and daily CHD mortality between 2001 and 2004 in Shanghai, China. Specifically, we used exposures averaged over periods varying from 1 to 5 days to assess the effects of DTR on CHD mortality. We estimated the percent increase in the number of daily deaths related to CHD that were associated with DTR, after adjustment for daily meteorologic conditions (temperature and relative humidity) and levels of outdoor air pollutants. Results: Both time-series and case-crossover analyses showed that DTR was significantly associated with the number of daily deaths related to CHD. A 1 °C increase in 2-day lagged DTR corresponded to a 2.46% (95% CI, 1.76% to 3.16%) increase in CHD mortality on time-series analysis, a 3.21% (95% CI, 2.23% to 4.19%) increase on unidirectional case-crossover analysis, and a 2.13% (95% CI, 1.04% to 3.22%) increase on bidirectional casecrossover analysis. Conclusions: Our findings suggest that DTR is an independent risk factor for acute CHD death.

AB - Background: Although the relation between day-to-day temperature change and coronary heart disease (CHD) mortality is well established, it is unknown whether temperature variation within 1 day, ie, diurnal temperature range (DTR), is an independent risk factor for acute CHD death. Methods: We used time-series and case-crossover approaches to assess the relation between DTR and daily CHD mortality between 2001 and 2004 in Shanghai, China. Specifically, we used exposures averaged over periods varying from 1 to 5 days to assess the effects of DTR on CHD mortality. We estimated the percent increase in the number of daily deaths related to CHD that were associated with DTR, after adjustment for daily meteorologic conditions (temperature and relative humidity) and levels of outdoor air pollutants. Results: Both time-series and case-crossover analyses showed that DTR was significantly associated with the number of daily deaths related to CHD. A 1 °C increase in 2-day lagged DTR corresponded to a 2.46% (95% CI, 1.76% to 3.16%) increase in CHD mortality on time-series analysis, a 3.21% (95% CI, 2.23% to 4.19%) increase on unidirectional case-crossover analysis, and a 2.13% (95% CI, 1.04% to 3.22%) increase on bidirectional casecrossover analysis. Conclusions: Our findings suggest that DTR is an independent risk factor for acute CHD death.

KW - Case-crossover

KW - Coronary heart disease

KW - Diurnal temperature range

KW - Mortality

KW - Time-series

UR - http://www.scopus.com/inward/record.url?scp=74249097565&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74249097565&partnerID=8YFLogxK

U2 - 10.2188/jea.JE20080074

DO - 10.2188/jea.JE20080074

M3 - Article

C2 - 19749499

AN - SCOPUS:74249097565

VL - 19

SP - 328

EP - 332

JO - Journal of Epidemiology

JF - Journal of Epidemiology

SN - 0917-5040

IS - 6

ER -