TY - JOUR
T1 - Distribution-based estimates of minimal important difference for hospital anxiety and depression scale and impact of event scale-revised in survivors of acute respiratory failure
AU - Chan, Kitty S.
AU - Aronson Friedman, Lisa
AU - Bienvenu, O. Joseph
AU - Dinglas, Victor D.
AU - Cuthbertson, Brian H.
AU - Porter, Richard
AU - Jones, Christina
AU - Hopkins, Ramona O.
AU - Needham, Dale M.
N1 - Funding Information:
This research was supported by the NHLBI (R24 HL111895, R01HL091760, R01HL091760-02S1, R01HL096504, and P050HL73994), the Johns Hopkins Institute for Clinical and Translational Research (ICTR) (UL1 TR 000424-06) and the ALTA and EDEN/OMEGA trials (contracts for sites participating in this study: HSN268200536170C, HHSN268200536171C, HHSN268200536173C, HHSN268200536174C, HSN268200536175C, and HHSN268200536179C). CESAR was supported by the UK NHS Health Technology Assessment, English National Specialist Commissioning Advisory Group, Scottish Department of Health and Welsh Department of Health. The PRaCTICaL study was funded by the Chief Scientist Office of the Scottish Executive Health Department (# CZH/4/351). The study by Jones et al. was supported, in part, by the Stanley Thomas Johnson Foundation, Berne, Switzerland and REMEDI, UK. The authors thank Dr. Elizabeth Colantuoni for guidance on the statistical methods used in this study. The authors have no conflicts of interests to report.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Objective This study will estimate distribution-based minimal important difference (MID) for the Hospital Anxiety and Depression Scale anxiety (HADS-A) and depression (HADS-D) subscales, and the Impact of Event Scale-Revised (IES-R) in survivors of acute respiratory failure (ARF). Methods Secondary analyses of data from two US and three UK studies of ARF survivors (total N=1223). HADS-D and HADS-A were used to assess depression and anxiety symptoms. IES-R assessed post-traumatic stress disorder symptoms. Standard error of measurement, minimal detectable change90, 0.5 standard deviation (S.D.), and 0.2 S.D. were used to estimate MID for the combined sample, by studies, 6- and 12-month follow-ups, country and mental health condition. Results Overall, MID estimates converged to 2.0–2.5 for the HADS-A, 1.9–2.3 for the HADS-D and 0.17–0.18 for the IES-R. MID estimates were comparable across studies, follow-up, country and mental health condition. Conclusion Among ARF survivors, 2.0–2.5 is a reasonable range for the MID for both HADS subscales, and 0.2 is reasonable for IES-R. Until anchor-based MIDs for these instruments are available, these distribution-based estimates can help researchers plan future studies and interpret the clinical importance of findings in ARF patient populations.
AB - Objective This study will estimate distribution-based minimal important difference (MID) for the Hospital Anxiety and Depression Scale anxiety (HADS-A) and depression (HADS-D) subscales, and the Impact of Event Scale-Revised (IES-R) in survivors of acute respiratory failure (ARF). Methods Secondary analyses of data from two US and three UK studies of ARF survivors (total N=1223). HADS-D and HADS-A were used to assess depression and anxiety symptoms. IES-R assessed post-traumatic stress disorder symptoms. Standard error of measurement, minimal detectable change90, 0.5 standard deviation (S.D.), and 0.2 S.D. were used to estimate MID for the combined sample, by studies, 6- and 12-month follow-ups, country and mental health condition. Results Overall, MID estimates converged to 2.0–2.5 for the HADS-A, 1.9–2.3 for the HADS-D and 0.17–0.18 for the IES-R. MID estimates were comparable across studies, follow-up, country and mental health condition. Conclusion Among ARF survivors, 2.0–2.5 is a reasonable range for the MID for both HADS subscales, and 0.2 is reasonable for IES-R. Until anchor-based MIDs for these instruments are available, these distribution-based estimates can help researchers plan future studies and interpret the clinical importance of findings in ARF patient populations.
KW - Acute respiratory failure
KW - Hospital anxiety and depression scale
KW - Impact of event scale-revised
KW - Minimal important difference
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U2 - 10.1016/j.genhosppsych.2016.07.004
DO - 10.1016/j.genhosppsych.2016.07.004
M3 - Article
C2 - 27638969
AN - SCOPUS:84979496778
VL - 42
SP - 32
EP - 35
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
SN - 0163-8343
ER -