Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru

Niyaz Ahmed; Luz Caviedes; Mahfooz Alam; K. Rajender Rao; Vartul Sangal; Patricia Sheen; Robert H. Gilman; Seyed E. Hasnain

doi:10.1128/JCM.41.4.1712-1716.2003

Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru

Niyaz Ahmed, Luz Caviedes, Mahfooz Alam, K. Rajender Rao, Vartul Sangal, Patricia Sheen, Robert H. Gilman, Seyed E. Hasnain

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (n = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.

Original language	English (US)
Pages (from-to)	1712-1716
Number of pages	5
Journal	Journal of clinical microbiology
Volume	41
Issue number	4
DOIs	https://doi.org/10.1128/JCM.41.4.1712-1716.2003
State	Published - Apr 1 2003

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/JCM.41.4.1712-1716.2003

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AU - Ahmed, Niyaz

AU - Caviedes, Luz

AU - Alam, Mahfooz

AU - Rao, K. Rajender

AU - Sangal, Vartul

AU - Sheen, Patricia

AU - Gilman, Robert H.

AU - Hasnain, Seyed E.

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AB - Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (n = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.

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Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru

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