Dissociation of Learning on Stimulant-Drug Therapy

Edward R.b. McCabe, Linda McCabe, Richard Allen, Daniel J. Safer

Research output: Contribution to journalLetter

Abstract

To the Editor: In addition to the observations of Safer, Allen and Barr1 of suppression of normal growth in hyperactive children treated with the stimulant drugs dextroamphetamine and methylphenidate, as well as the reports of other undesirable consequences,2 there is the possibility that such drug treatments will produce dissociated or state-dependent learning in these children. With complete dissociation of learning a person masters the required behavior in one drug state (which may be defined by the presence or absence of the drug) and subsequently exhibits that behavior only in the original drug state.3 It appears that the drug-produced cues present.

Original languageEnglish (US)
Pages (from-to)825
Number of pages1
JournalNew England Journal of Medicine
Volume287
Issue number16
DOIs
StatePublished - Oct 19 1972

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Learning
Drug Therapy
Pharmaceutical Preparations
Dextroamphetamine
Methylphenidate
Cues
Growth
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dissociation of Learning on Stimulant-Drug Therapy. / McCabe, Edward R.b.; McCabe, Linda; Allen, Richard; Safer, Daniel J.

In: New England Journal of Medicine, Vol. 287, No. 16, 19.10.1972, p. 825.

Research output: Contribution to journalLetter

McCabe, Edward R.b. ; McCabe, Linda ; Allen, Richard ; Safer, Daniel J. / Dissociation of Learning on Stimulant-Drug Therapy. In: New England Journal of Medicine. 1972 ; Vol. 287, No. 16. pp. 825.
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